Effects of static magnetic field on growth of leptospire, Leptospira interrogans serovar canicola: immunoreactivity and cell division.

Leptospire genomic diversity revealed by microarray-based comparative genomic hybridization.

Comparative genomic hybridization was used to compare genetic diversity of five strains of Leptospira (Leptospira interrogans serovars Bratislava, Canicola, and Hebdomadis and Leptospira kirschneri serovars Cynopteri and Grippotyphosa). The array was designed based on two available sequenced Leptospira reference genomes, those of L. interrogans serovar Copenhageni and L. interrogans serovar Lai...

Characterisation of the Proteome of Leptospira interrogans Serovar Canicola as a Resource for the Identification of Common Serovar Immunogenic Proteins

Over 230 serovars of Leptospira interrogans have been identified; however few have been completely characterised. The aim of this study was to characterise the proteome of serovar Canicola and to compare this against the serovars of Copenhageni and Pomona. 2D-LC/MS analysis identified 1653 Leptospira proteins in serovar Canicola; 60 of these proteins were common to Copenhageni and Pomona, 16 of...

Cloning and Expression of Antigen Genes of Leptospira Interrogans Serovar Canicola in Escherichia Coli, and Restriction Endonuclease Dna Analysis of Antigenic Variants of Leptospires Selected by Monoclonal Antibodies

Vaccination with leptospiral outer membrane lipoprotein LipL32 reduces kidney invasion of Leptospira interrogans serovar canicola in hamsters.

The Leptospira interrogans vaccines currently available are serovar specific and require regular booster immunizations to maintain protection of the host. In addition, a hamster challenge batch potency test is necessary to evaluate these vaccines prior to market release, requiring the use of a large number of animals, which is ethically and financially undesirable. Our previous work showed that...

Serologic study on leptospiral infection in sheep in Ahvaz, southwestern Iran

To investigate the seroprevalence of leptospiral infection in sheep in Ahvaz, southwestern Iran, bloodsamples were taken from 181 female sheep. Sera were stored at -20°C until use. They were initially screenedat serum dilution of 1:100 against six live antigens of Leptospira interrogans serovars pomona, canicola,hardjo, ballum, icterohaemorrhagiae, grippotyphosa using the microscopic agglutinat...